XtalPi Inc. (XtalPi Holdings-P, XTALPI-P, stock code: 2228.HK) has entered into a strategic collaboration with Deep Principle, a rising star in AI-driven chemistry. The partnership harnesses XtalPi’s AI and robotics platform alongside both parties’ strengths to advance intelligent and automated R&D in chemical materials. Together, they aim to develop a next-generation, full-chain intelligent materials R&D platform that integrates novel molecular design, reaction pathway optimization, synthesis enhancement, and high-throughput automated workstations. This will enable a complete closed-loop process—from material discovery and property prediction to formulation optimization and controlled experimentation—in shorter timelines, establishing a “faster, more accurate, and cost-effective” new paradigm for research.
Also originating from MIT, Deep Principle was co-founded by CEO Dr. Jia Haojun and CTO Dr. Duan Chenru. The company is dedicated to accelerating materials chemistry innovation through AI, leveraging decision-making models and generative AI in chemical reactions to disrupt the traditional “top-down trial-and-error” approach to chemical material discovery.
As Deep Principle’s strategic investor, XtalPi provides not only capital support but also technical and commercialization expertise to jointly accelerate the development of new chemical reactions and materials. This collaboration will unlock broader chemical spaces and innovative synthesis pathways, expediting the development and market deployment of new technologies and molecules.
Following the announcements of the 2024 Nobel Prizes in Physics and Chemistry, artificial intelligence has once again captured widespread attention. As a general-purpose technology, AI is transitioning from labs to industrial applications across sectors, leading technological advancements, transforming research paradigms, and empowering diverse industries.
As a pioneer in scaling AI applications in biopharmaceuticals and expanding into new materials, fine chemicals, and renewable energy, XtalPi leverages quantum physics, AI empowerment, and robotics to develop an AI-robotics innovation platform for future industries. The company has achieved breakthroughs in intelligent chemistry (AI for Chemistry) and intelligent materials (AI for Materials).
To extend the benefits of cutting-edge innovations across domains, XtalPi, as a platform enterprise, has built a comprehensive technology service ecosystem integrating innovative technologies, models, and high-quality data. On one hand, it has established and scaled AI-robotics labs from the ground up, continuously generating and accumulating real-world experimental data. Using this data, XtalPi has developed and trained multiple vertical-domain models, delivering tangible value in specific industries and earning recognition from global clients.
On the other hand, XtalPi engages in deep exchanges and collaborations with top global research institutions, fostering synergy between academia and industry to translate innovations from labs to markets. Examples include partnering with MIT’s Department of Chemistry to explore AI and robotics-driven paradigms for AI for Science in chemistry and materials research, and collaborating with Singapore’s Experimental Drug Development Centre (EDDC) on innovative therapies for non-small cell lung cancer.
Simultaneously, XtalPi shares its proprietary platforms with partners, collaborating with domain experts to address industry-specific challenges. Notable efforts include co-building an AI4S drug discovery ecosystem with Deep Potential; advancing new drug R&D with Yaosu Technology via AI and organ-on-a-chip; tackling “green production” and “quality enhancement” in catalyst development with Sinopec Shanghai Research Institute; and promoting “green, efficient R&D” for high-tech new energy materials with GCL Group.
XtalPi continues to refine its AI and robotic experimentation technologies, exploring new application frontiers and expanding the reach of its innovation platform. By partnering with academia, industry, and research communities, XtalPi is building a technological and innovative river for the digital transformation of future industries.
