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Biotech insights for the future

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Case Studies

Biotech, Case Studies, Small Molecule Drug Discovery

Hit Identification – SARM1 Structural Elucidation By Internal Cryo-EM Platform

Case Studies, Small Molecule Drug Discovery

Identifying Novel FGFR3 Inhibitors By XtalPi-Curated HTS Diversity Library

Biotech, Case Studies, Small Molecule Drug Discovery

Hit Identification – Novel Hits for GPX4

Biotech, Case Studies, Small Molecule Drug Discovery

Lead Identification – Discovering Selective Inhibitors Against an Unreported Binding Pocket of SMARCA2 via a Rational Drug Design Approach

Application Notes, Solid State Research

Elucidate the Crystal Structure of a Poorly Crystalline Compound in 2 Weeks with MicroED and Targeted CSP

Application Notes, Case Studies, Solid State Research

Crystal Structure Prediction (CSP) De-risks Polymorph Instability by Providing a Deep Insight Into All Stable Forms

Case Studies, Solid State Research

Enhanced Salt Screening With Rational Experimental Design Guided by Salt Formation Propensity Prediction Model

Case Studies, Software, XFEP

Development of small molecule selective inhibitors with XFEP

Application Notes, Solid State Research

Elucidate the Crystal Structure of a Poorly Crystalline Compound in 2 Weeks with MicroED and Targeted CSP

Application Notes, Case Studies, Solid State Research

Crystal Structure Prediction (CSP) De-risks Polymorph Instability by Providing a Deep Insight Into All Stable Forms

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Publications

Publications, Solid State Research

Templated Nucleation of Clotrimazole and Ketoprofen on Polymer Substrates

Publications, Small Molecule Drug Discovery, Solid State Research

Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid)

Publications, Solid State Research

Cocrystal Synthesis through Crystal Structure Prediction

Publications, Solid State Research, Solid State Research

Effect of Polymer Additives on the Crystal Habit of Metformin HCl

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Video Library

Video Library

Unlock Faster, Smarter Polymorph Screening with XtalGazer™ CSP

Video Library

Unlock Faster, More Accurate Drug Discovery with XFEP

Solid-State R&D Series, Video Library

Intelligent Cloud-Based Algorithms for Pharmaceutical Drug Formulation and Development

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News & Events

News

XtalPi Announces Strategic Partnership with a Leading Biopharma to Develop Oral Small Molecule Therapeutics for a GPCR Target

News

Full Agenda Revealed: 2026 XtalPi AI-Driven Drug Discovery Innovation Summit

News

XtalPi Receives Second Payment from DoveTree; First Oncology Asset Advances into IND-Enabling Studies