Case Studies Archives - XtalPi

Case Studies

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Publications, Solid State Research

Templated Nucleation of Clotrimazole and Ketoprofen on Polymer Substrates

Publications, Solid State Research

Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid)

Publications, Solid State Research

Cocrystal Synthesis through Crystal Structure Prediction

Publications, Solid State Research, Solid State Research

Effect of Polymer Additives on the Crystal Habit of Metformin HCl

Application Notes, Solid State Research

Elucidate the Crystal Structure of a Poorly Crystalline Compound in 2 Weeks with MicroED and Targeted CSP

Application Notes, Case Studies, Solid State Research

Crystal Structure Prediction (CSP) De-risks Polymorph Instability by Providing a Deep Insight Into All Stable Forms

Case Studies, Solid State Research

Enhanced Salt Screening With Rational Experimental Design Guided by Salt Formation Propensity Prediction Model

Case Studies, Software, XFEP

Development of small molecule selective inhibitors with XFEP

Case Studies, Software, XFEP

Discovery of Novel Non-covalent GPX4 Potent Hits with XFEP

Case Studies, Software, XFEP, XmolGen

Discovery of Novel Leads Targeting a Highly Flexible Allosteric Site with XMolGen and XFEP

Case Studies, PatSight, Software

Extract 1500 structures and activity data within one hour

Biotech, Case Studies, Small Molecule Drug Discovery

Hit Identification – SARM1 Structural Elucidation By Internal Cryo-EM Platform

Case Studies, Small Molecule Drug Discovery

Identifying Novel FGFR3 Inhibitors By XtalPi-Curated HTS Diversity Library

Biotech, Case Studies, Solid State Research

How XtalPi Utilized MicroED to Tackle Different Polymorphism Challenges

Biotech, Case Studies, Solid State Research

Accelerated Identification of the Most Stable Remdesivir Polymorph in 33 Days Using an Integrated Experimental and Computational Approach

Biotech, Case Studies, Small Molecule Drug Discovery

Hit Identification – Novel Hits for GPX4

Biotech, Case Studies, Small Molecule Drug Discovery

Lead Identification – Discovering Selective Inhibitors Against an Unreported Binding Pocket of SMARCA2 via a Rational Drug Design Approach